A 2026 comparative study examines reproductive outcomes after different frozen embryo transfer protocols.

The study compared programmed ovulatory cycles with modified natural cycles using an analysis adjusted for patient characteristics. The findings add information for individualized endometrial preparation, while the observational design means associations should be interpreted cautiously.

What it means for practice

Protocol choice still depends on clinical circumstances, ovulation and local expertise. The results support personalized decision-making rather than establishing one universally superior approach.

Source: PubMed / Fertility and Sterility