A 2026 meta-analysis reviews how unilateral endometriomas may relate to ovarian response during fertility treatment.

The analysis brings together studies examining the effect of endometriomas on stimulation and ovarian-response measures. The findings can help contextualize decisions when assisted reproduction is being planned.

What it means for practice

An endometrioma alone does not determine treatment strategy. Ovarian reserve, lesion size and location, symptoms and reproductive goals should be considered together.

Source: Human Reproduction