A 2026 prospective study examines whether central sensitization may be associated with poorer response to hormonal treatment for endometriosis-related pain.

The research addresses the complexity of pelvic pain and examines nervous-system sensitization features in relation to symptom evolution.

What it means for practice

The findings support multidimensional pain assessment. Treatment response may depend on mechanisms that extend beyond visible gynecological lesions.

Source: Journal of Minimally Invasive Gynecology / PubMed